Tuesday , April 20 2021

Stress is said to be a source of worsening allergies!

In a recent study, Japanese researchers show that stress and psychological tension are aggravating factors for allergies. According to study leaders, the increase in allergic reactions is related to a specific hormone.

Guilty: corticotropin

What if stress increases allergic reactions? Professor Mika Yamanaka-Takaichi from Osaka University (Japan) agrees, as evidenced by the publication of the study at the International Journal of Molecular Sciences March 9, 2021. The person concerned states in his report that he encounters in daily practice many patients who worsen allergy symptoms. due to psychological stress.

Mika Yamanaka-Takaichi recalls that any stressful situation is a source of corticotropin production (or adrenocorticotropic hormone – ACTH). However, the work of the researcher creates a link between this hormone and the proliferation of mast cells. These are oval cells called nasal allergies. It is therefore a “mixture” the presence of exacerbated allergies.

This work could make it possible better understand the origin of allergies, and therefore find treatments that can effectively overcome it. Mika Yamanaka-Takaichi also mentioned the discovery of promising therapeutic potential in certain candidates, such as antalarmine. The latter is none other than medicine acts as an antagonist corticotropin-releasing hormone CRH1.

Credit: cenzi7 / Wikipedia

Major public health problem

According to Inserm 25-35% of the world’s population affected by an allergic disease. Anyone can suffer from it, especially children and young adults, and variations vary by country and age. Two conditions are necessary, namely a genetic predisposition and, of course, exposure to an allergenic substance.

The World Health Organization (WHO) ranks allergic diseases 4th in the world for chronic diseases. He likes them besides significant public health problem and highlights the impact on quality of life, loss of work or teaching days, cost of care, and mortality in certain cases.

These allergies – especially seasonal ones – tend to increase. According to forecasts, by 2050 half of the world’s population is “allergic to someone” compared to less than 5 percent half a century ago.

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