Is tinnitus curable in the near future?
A number of US researchers have now announced that they have found a groundbreaking treatment for tinnitus. They discovered that the TNF-A molecule appears to interfere with neuronal communication between interfering tinnitus. This observation could enable the development of new treatments for tinnitus.
Arizona University's current study found that blocking a particular protein prevents tinnitus. The results of the study were published in the English-language journal PLOS Biology.
What is tinnitus?
Tinnitus is a condition where you notice ears that are not from a regular source, including ringing tones, buzzing, and pulsating. Tinnitus can cause stress, sleep disturbances, anxiety and hearing loss, and is often associated with Meniere's disease, diabetes, multiple sclerosis and depression. So far, there is no cure for the disease.
Neuro Inflammation For Tinnitus Treatment?
University of Arizona researchers have now managed to stop tinnitus in mice (who developed tinnitus after two hours of exposure to noise) by blocking the brain's pro-inflammatory protein. The results suggest that the so-called. Neuro inflammation can be a therapeutic target for the treatment of tinnitus and other hearing problems. Genetic fallout or pharmacological inhibition of TNF-A would prevent inflammation of the nervous system and improved tinnitus-induced behavior in mice with noise-induced hearing loss. The group analysis showed that in the brain processing area, inflammation caused a controlled ringing in the ears of the affected mice.
Hearing loss is a major risk factor for tinnitus
Hearing loss is a widespread disease affecting around 500 million people worldwide and is a major risk factor for tinnitus. Recent studies suggest that hearing loss is due to inflammation of the ear canal, which is the immune system's response to injury and infection. However, how this affects hearing-related diseases such as tinnitus is still poorly known. The results suggest that noise-induced hearing loss is associated with increased levels of molecules called proinflammatory cytokines, and activation of non-neuronal cells, called microglia, in the primary ear canal, the authors of the study explain.
More research is needed
These results refer to neuroinflammation as a therapeutic target for the treatment of tinnitus and other hearing-related disorders. Although the treatment used was successful in animals, possible side effects should be thoroughly investigated before the first human studies are performed, researchers say. (Flat)
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