Monday , October 26 2020

Was the juvenile fountain examined? Long-term life expectancy by injecting this protein

How Infusion Can Increase Life Expectancy

Can I use blood-borne protein in the future to increase my total duration? Scientists have now found that injecting younger mice with blood seems to be a kind of young fountain for older mice. The infusion meant that the life expectancy of the animals increased by almost 20%.

A recent study by the University of Washington, University of Medicine, St. Louis, Missouri, found that the protein in the blood of young mice injected into older mice improves the life of older animals. The results of the study were published in the English journal "Cell Metabolism".

Can a particular protein infusion contribute to a longer life or a younger person in the future? (Photo: master1305 /

What is eNAMPT?

The ENAMPT protein found in the blood of younger mice can keep older rodents healthy and longer. Older mice with protein improved cognitive function and sleep quality, and the animals had a life expectancy of nearly 20 percent. In humans, this corresponds to a massive increase in life expectancy from 79 to 91 years, the authors report. The results suggest that this method can be a secret and an aging method for the prevention of aging-related diseases in humans. ENAMPT usually plays a role in energy production. However, as the body ages, the cells lose their efficiency in producing this energy called NAD, the researchers explain. Since it is known that NAD will inevitably decrease with age, many researchers are interested in finding anti-aging measures that can maintain NAD levels in old age.

eNAMPT clearly increases life expectancy

In this study, one of the older mice was given a concentrated eNAMPT from younger mice and another group received saline. All mice in the saline receiving group died within about 2.4 years, while the animals given eNAMPT lived for about 2.8 years. This means that the body protein of the mice in the protein group was about 16% higher than in the control group animals. Older mice with a higher concentration of this blood component also had a better quality of sleep, improved cognitive function in memory tests, and ran more into cages. It should be noted that eNAMPT can be taken from the blood of young mice and given to older mice, leading to significantly improved health of older mice, including increased physical activity and better sleep, researchers add.

What is the role of the hypothalamus?

The reason why we are aging faster when the protein is weak is probably related to the hypothalamus, the authors speculate. Hypothalamus is an area of ​​the brain that is known to be important for social behavior and hormone production. It is largely regulated by the protein studied. Recently, it has been found that hypothalamic stem cells control the body's aging process. Since the level of the studied key protein decreases during aging, the hypothalamus no longer works, which is why the life span is shortened, researchers doubt it. For future research, the team wants to find out whether the low level of eNAMPT protein is related to the elderly and whether it can be used to prevent aging. (Flat)


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