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Capital | Ask to change the drug for effective tuberculosis treatment



Every year 600 000 cases of many drugs (MDR-TB) are identified, of which 240 000 are fatal

06/11/2018

Notimex agency

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Montreal. – Existing treatment practices for the prevention of tuberculosis must be thoroughly examined before the emergence of new, more effective medicines to combat it.

According to the results of the new international study conducted by Dr McGill University Health Center Research Center in Montreal, Dr. Dick Menzies, a comprehensive overview of the treatment of multiple tumor-resistant tuberculosis should be carried out.

Every year, 600,000 multi-dimensional TB (MDR-TB) is identified, of which 240,000 are fatal.

Diagnosis and treatment are an overwhelming challenge; In fact, in patients with this disease, only one out of four cases are diagnosed and the proportion of patients treated is even lower.

The study concluded that new drugs to combat multi-use tuberculosis are more effective than traditional medicines.

MDR-TB's current therapies include expensive long-term medications with adverse side effects such as persistent nausea, loss of hearing, and renal failure, according to Radio Canada International (RCI).

McGill University Researcher and Pulmonologist, MD Menzies, US, Europe, Latin America, and Asia Pacific, combines data with over 12,000 MDR-TB patients. this information comes from 50 studies in 25 countries.

Creating such a large amount of data allowed scientists to conclude that drugs used to treat tuberculosis such as bedaquil, linezolid and high-end drugs such as fluoroquinolones are excellent candidates for MDR-TB.

According to Dr. Menzies's team, these new drugs lead to better healing and lower mortality compared to current treatments.

The World Health Organization (WHO) has already responded to the findings of the research team led by Menzies by completing its conclusions.

"The committee responsible for the guidelines simply removed the recommendations from previous treatments and started out of scratch, which made a 180 degree translation of TB," says Menzies, an RI-MUHC translator research program for respiratory diseases and a professor of medicine, epidemiology and biostatistics at McGill University.

Pulmonary tuberculosis is the deadliest infectious disease in the world and one of the hottest 10 deaths, despite the fact that the prevalence of tuberculosis has declined globally since the early 2000s.

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