coffee: do you love coffee? It feels that it can protect you against the development of Alzheimer's and Parkinson's

WASHINGTON D.C. [USA]: Do you love coffee? It feels that good in that morning can be more than energy and eye-catching. Drinking water can protect yourself against the development of Alzheimer's and Parkinson's disease.

According to a new study, about 500 billion cups of coffee are consumed annually. The results of the study are published in the Journal of Frontiers in Neuroscience

"Coffee consumption seems to have some correlation with the risk of Alzheimer's and Parkinson's disease decline," says researcher Donald Weaver. "But we wanted to investigate why this is – which compounds are involved and how they can affect age-related cognitive impairment."


The research team decided to study three different types of coffee – light fried, dark roast and decaffeinated dark roast.

"The caffeine and caffeine-rich dark roasts had identical potentials in their original trials," says researcher Ross Dr. Mancini. "So we soon discovered that its protective effect can not be due to caffeine."

Dr. Mancini then identified a group known as phenylindans, which resulted from the roasting process of coffee beans. Phenylindans are unique because they are the only compound studied in the study that inhibits – or rather blocks – both beta-amyloid and tau proteins that are common in protein defects of Alzheimer's and Parkinson's disease. "Thus, the phenylindans are a double inhibitor. Very interesting, we did not expect it," said Dr. Weaver.


When roasting results in a greater number of phenylsulphates, dark roasted coffee appears to be more protective than light roasted coffee.

"It's the first time anyone investigates how the phenylenides interact with Alzheimer's and Parkinson's," says Dr. Mancini. "The next step would be to study how useful these compounds are, and whether they have the ability to reach the bloodstream or cross the blood brain barrier."

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